Spontaneous aortic sealing with tranexamic acid in type a dissection: a novel life-saving finding

This case highlights a potentially important role for tranexamic acid (TXA) in the management of aortic dissection. To our knowledge, this is the first reported case of its kind.While its established use in reducing postoperative bleeding and transfusion requirements is well documented, our case demonstrates a preoperative benefit, with TXA contributing to the formation of a stabilizing thrombus within the dissected aortic segment.This life-saving clot prevented further dissection and haemorrhage, ultimately deferring the need for surgical repair and reducing the risk of perioperative complications.We aim to underscore the need for further investigation into the potential role of tranexamic acid in the acute management of aortic dissection.

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Publication Details

Journal
European Journal of Case Reports in Internal Medicine
Published
2025-08-18
DOI
https://doi.org/10.12890/2025_005650
Citations
1
Primary Topic
Aortic Disease and Treatment Approaches
Type
article
Field-Weighted Citation Impact
1.52
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article

Spontaneous aortic sealing with tranexamic acid in type a dissection: a novel life-saving finding

Elias Fiani, Karam Karam, Antonio Al Hazzouri, Philippe Attieh
1 citations
European Journal of Case Reports in Internal Medicine
Aortic Disease and Treatment Approaches
1.52
article

Spontaneous aortic sealing with tranexamic acid in type a dissection: a novel life-saving finding

Elias Fiani, Karam Karam, Antonio Al Hazzouri, Philippe Attieh
article en
1 citations

Abstract

This case highlights a potentially important role for tranexamic acid (TXA) in the management of aortic dissection. To our knowledge, this is the first reported case of its kind.While its established use in reducing postoperative bleeding and transfusion requirements is well documented, our case demonstrates a preoperative benefit, with TXA contributing to the formation of a stabilizing thrombus within the dissected aortic segment.This life-saving clot prevented further dissection and haemorrhage, ultimately deferring the need for surgical repair and reducing the risk of perioperative complications.We aim to underscore the need for further investigation into the potential role of tranexamic acid in the acute management of aortic dissection.

European Journal of Case Reports in Internal MedicineVol. 12(9)
University of Balamand (LB)
Openalex Percentile: Top 15%
Aortic Disease and Treatment Approaches
1.52
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Spontaneous aortic sealing with tranexamic acid in type a dissection: a novel life-saving finding — Elias Fiani, Karam Karam, et al. · European Journal of Case Reports in Internal Medicine (2025) | TGRS Research Map | TGRS