Spontaneous aortic sealing with tranexamic acid in type a dissection: a novel life-saving finding
This case highlights a potentially important role for tranexamic acid (TXA) in the management of aortic dissection. To our knowledge, this is the first reported case of its kind.While its established use in reducing postoperative bleeding and transfusion requirements is well documented, our case demonstrates a preoperative benefit, with TXA contributing to the formation of a stabilizing thrombus within the dissected aortic segment.This life-saving clot prevented further dissection and haemorrhage, ultimately deferring the need for surgical repair and reducing the risk of perioperative complications.We aim to underscore the need for further investigation into the potential role of tranexamic acid in the acute management of aortic dissection.
Authors
- Elias Fiani (ORCID: https://orcid.org/0000-0003-3204-9098)
- Karam Karam (ORCID: https://orcid.org/0009-0001-1914-320X)
- Antonio Al Hazzouri
- Philippe Attieh (ORCID: https://orcid.org/0009-0006-8491-0790)
Institutions
- University of Balamand (LB)
Publication Details
- Journal
- European Journal of Case Reports in Internal Medicine
- Published
- 2025-08-18
- DOI
- https://doi.org/10.12890/2025_005650
- Citations
- 1
- Primary Topic
- Aortic Disease and Treatment Approaches
- Type
- article
- Field-Weighted Citation Impact
- 1.52