Predictive value of traditional laboratory parameters and inflammatory indices for same‐day seizure recurrence in patients with epileptic seizures

This study looked at whether certain blood test values can help predict if a person who comes to the emergency department (ED) with an epileptic seizure will have another seizure on the same day. Researchers focused on inflammation-related markers found in routine blood tests, such as the neutrophil-to-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII). We found that these values were higher in patients who had repeated seizures within the same day. However, while these markers showed some association with seizure recurrence, they were not accurate enough to reliably predict it on their own. These findings suggest that simple blood tests might provide helpful clues in emergency settings, but more research is needed to find stronger and more reliable indicators for early seizure recurrence.

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Publication Details

Journal
Epilepsia Open
Published
2025-08-18
DOI
https://doi.org/10.1002/epi4.70123
Citations
1
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
1.47
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article

Predictive value of traditional laboratory parameters and inflammatory indices for same‐day seizure recurrence in patients with epileptic seizures

Murat Alemdar, Elif Sarıca Darol, Alaaddin Polat
1 citations
Epilepsia Open
Epilepsy research and treatment
1.47
article

Predictive value of traditional laboratory parameters and inflammatory indices for same‐day seizure recurrence in patients with epileptic seizures

Murat Alemdar, Elif Sarıca Darol, Alaaddin Polat
article en
1 citations

Abstract

This study looked at whether certain blood test values can help predict if a person who comes to the emergency department (ED) with an epileptic seizure will have another seizure on the same day. Researchers focused on inflammation-related markers found in routine blood tests, such as the neutrophil-to-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII). We found that these values were higher in patients who had repeated seizures within the same day. However, while these markers showed some association with seizure recurrence, they were not accurate enough to reliably predict it on their own. These findings suggest that simple blood tests might provide helpful clues in emergency settings, but more research is needed to find stronger and more reliable indicators for early seizure recurrence.

Epilepsia OpenVol. 10(5)
Sakarya University (TR), Sakarya Eğitim ve Araştırma Hastanesi (TR)
Reduced inequalities
Openalex Percentile: Top 16%
Epilepsy research and treatment
1.47
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