Non-linear association between neutrophil-to-lymphocyte ratio and 90-day mortality in patients with pneumonia receiving glucocorticoids alone or in combination with other immunosuppressants: A retrospective cohort study

A nonlinear correlation between NLR and 90-day mortality was identified in pneumonia patients undergoing glucocorticoid treatment. The NLR value of 16.475 represented the optimal threshold for predicting the 90-day mortality, after exceeding the threshold,90-day mortality tended to stabilize. The findings suggest that NLR is a practical and useful biomarker for predicting the 90-day mortality in this population.

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Journal
PLoS ONE
Published
2025-08-18
DOI
https://doi.org/10.1371/journal.pone.0329616
Primary Topic
Pneumonia and Respiratory Infections
Type
article
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article

Non-linear association between neutrophil-to-lymphocyte ratio and 90-day mortality in patients with pneumonia receiving glucocorticoids alone or in combination with other immunosuppressants: A retrospective cohort study

Caizhen Chen, Geng Qian, Xiuguo Zhang, Baoli Li
PLoS ONE
Pneumonia and Respiratory Infections
article

Non-linear association between neutrophil-to-lymphocyte ratio and 90-day mortality in patients with pneumonia receiving glucocorticoids alone or in combination with other immunosuppressants: A retrospective cohort study

Caizhen Chen, Geng Qian, Xiuguo Zhang, Baoli Li
article en

Abstract

A nonlinear correlation between NLR and 90-day mortality was identified in pneumonia patients undergoing glucocorticoid treatment. The NLR value of 16.475 represented the optimal threshold for predicting the 90-day mortality, after exceeding the threshold,90-day mortality tended to stabilize. The findings suggest that NLR is a practical and useful biomarker for predicting the 90-day mortality in this population.

PLoS ONEVol. 20(8)
Hebei Medical University (CN), Third Hospital of Hebei Medical University (CN)
Openalex Percentile: Top 71%
Pneumonia and Respiratory Infections
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Non-linear association between neutrophil-to-lymphocyte ratio and 90-day mortality in patients with pneumonia receiving glucocorticoids alone or in combination with other immunosuppressants: A retrospective cohort study — Caizhen Chen, Geng Qian, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS