Cholestasis associated microtrabecular and pseudoacinar morphologies in hepatocellular carcinoma: Predicting immunophenotypes, clinical, and radiological outcome
We propose that HCCs showing strong GS expression and cholestasis irrespective of microtrabecular, pseudoacinar, or mixed pattern should be subjected to further beta-catenin analysis by IHC and molecular testing to categorize them as CTNNB1-mutated tumors as they have prognostic and predictive values.
Authors
- Sudipta Mohakud
- Mukund Sable (ORCID: https://orcid.org/0000-0003-1547-8595)
- Manas Panigrahi (ORCID: https://orcid.org/0000-0002-3639-8386)
- Susama Patra
- Shalini Chaudhary (ORCID: https://orcid.org/0009-0009-3669-7149)
- Subash Chandra Samal
- Chinmayee Panigrahi
- Ajit Sahu
Institutions
- Department of Health & Family Welfare (IN)
- All India Institute of Medical Sciences Bhubaneswar (IN)
Publication Details
- Journal
- Indian Journal of Pathology and Microbiology
- Published
- 2025-08-14
- DOI
- https://doi.org/10.4103/ijpm.ijpm_954_24
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00