Hybrid intercalated duct lesion in conjunction with pleomorphic adenoma: A rare co-existence

Intercalated ductal lesions (IDL) are the rare lesions of salivary glands. These lesions range from ductal hyperplasia to adenomas. The first case was reported nearly three decades ago, yet very few cases are available in the literature. Many researchers postulate these lesions as precursors of other salivary malignancies, while few studies show mutations in CTNNB1 and HRAS genes. The causative factors of these lesions and their association with other lesions of salivary glands need to be studied further. Here, we present a case report of pleomorphic adenoma with IDL, which could be a drop in a future ocean of these lesions.

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Journal
Indian Journal of Pathology and Microbiology
Published
2025-08-14
DOI
https://doi.org/10.4103/ijpm.ijpm_24_24
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
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article
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article

Hybrid intercalated duct lesion in conjunction with pleomorphic adenoma: A rare co-existence

Tushar Parmeshwar, Sumitra Sivakoti, Naveen chand Perugu, G.P. Rathod
Indian Journal of Pathology and Microbiology
Salivary Gland Tumors Diagnosis and Treatment
article

Hybrid intercalated duct lesion in conjunction with pleomorphic adenoma: A rare co-existence

Tushar Parmeshwar, Sumitra Sivakoti, Naveen chand Perugu, G.P. Rathod
article en

Abstract

Intercalated ductal lesions (IDL) are the rare lesions of salivary glands. These lesions range from ductal hyperplasia to adenomas. The first case was reported nearly three decades ago, yet very few cases are available in the literature. Many researchers postulate these lesions as precursors of other salivary malignancies, while few studies show mutations in CTNNB1 and HRAS genes. The causative factors of these lesions and their association with other lesions of salivary glands need to be studied further. Here, we present a case report of pleomorphic adenoma with IDL, which could be a drop in a future ocean of these lesions.

Indian Journal of Pathology and MicrobiologyVol. 68(4)
All India Institute of Medical Sciences (IN)
Life below water
Openalex Percentile: Top 65%
Salivary Gland Tumors Diagnosis and Treatment
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Hybrid intercalated duct lesion in conjunction with pleomorphic adenoma: A rare co-existence — Tushar Parmeshwar, Sumitra Sivakoti, et al. · Indian Journal of Pathology and Microbiology (2025) | TGRS Research Map | TGRS