Risk factors for the progression of distal adding-on phenomenon after surgery in patients with Lenke type 1 and 2 adolescent idiopathic scoliosis

To investigate risk factors associated with the progression of the distal adding-on phenomenon after posterior selective thoracic fusion in patients with Lenke type 1 and 2 adolescent idiopathic scoliosis (AIS). A retrospective analysis was conducted on 152 patients who underwent posterior selective thoracic fusion from December 2015 to December 2021. Among them, 48 patients experienced the distal adding-on phenomenon postoperatively. Based on whether this phenomenon progressed during follow-up, they were divided into progressive and non-progressive groups. Univariate analysis compared clinical and imaging data between the two groups, while multivariate logistic regression identified independent risk factors. Of the 48 patients with postoperative distal adding-on, 37 (77.1%) were non-progressive and 11 (22.9%) were progressive. Univariate analysis showed significant differences between the progressive and non-progressive groups in Risser sign grade (2.27 ± 1.10 vs. 3.73 ± 0.87, P < 0.001), number of segments between lowest instrumented vertebra (LIV) and the last substantially touched vertebra (LSTV) (-1.27 ± 0.79 vs. 0.51 ± 1.17, P < 0.001), preoperative clavicle angle (-2.55 ± 2.84 vs. -0.11 ± 2.82, P = 0.015), and preoperative trunk shift (21.05 ± 15.27 vs. 10.46 ± 13.32, P = 0.030). Multivariate analysis confirmed that lower Risser sign grade (OR = 0.16, 95% CI 0.03-0.82, P = 0.028) and fewer segments between LIV and LSTV (OR = 0.07, 95% CI 0.01-0.58, P = 0.013) were independent risk factors for the progression of the distal adding-on phenomenon. Lower skeletal maturity (Risser sign grade) and LIV located cephalad to LSTV are independent risk factors for the progression of the distal adding-on phenomenon in patients with Lenke type 1 and 2 AIS. For skeletally immature patients (Risser ≤ 3), LSTV should be preferentially chosen as LIV during surgery.

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Journal
Scientific Reports
Published
2025-08-18
DOI
https://doi.org/10.1038/s41598-025-15714-1
Primary Topic
Scoliosis diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Risk factors for the progression of distal adding-on phenomenon after surgery in patients with Lenke type 1 and 2 adolescent idiopathic scoliosis

Yubin Long, X B Wang, Yong Li, Tao Li
Scientific Reports
Scoliosis diagnosis and treatment
article

Risk factors for the progression of distal adding-on phenomenon after surgery in patients with Lenke type 1 and 2 adolescent idiopathic scoliosis

Yubin Long, X B Wang, Yong Li, Tao Li
article en

Abstract

To investigate risk factors associated with the progression of the distal adding-on phenomenon after posterior selective thoracic fusion in patients with Lenke type 1 and 2 adolescent idiopathic scoliosis (AIS). A retrospective analysis was conducted on 152 patients who underwent posterior selective thoracic fusion from December 2015 to December 2021. Among them, 48 patients experienced the distal adding-on phenomenon postoperatively. Based on whether this phenomenon progressed during follow-up, they were divided into progressive and non-progressive groups. Univariate analysis compared clinical and imaging data between the two groups, while multivariate logistic regression identified independent risk factors. Of the 48 patients with postoperative distal adding-on, 37 (77.1%) were non-progressive and 11 (22.9%) were progressive. Univariate analysis showed significant differences between the progressive and non-progressive groups in Risser sign grade (2.27 ± 1.10 vs. 3.73 ± 0.87, P < 0.001), number of segments between lowest instrumented vertebra (LIV) and the last substantially touched vertebra (LSTV) (-1.27 ± 0.79 vs. 0.51 ± 1.17, P < 0.001), preoperative clavicle angle (-2.55 ± 2.84 vs. -0.11 ± 2.82, P = 0.015), and preoperative trunk shift (21.05 ± 15.27 vs. 10.46 ± 13.32, P = 0.030). Multivariate analysis confirmed that lower Risser sign grade (OR = 0.16, 95% CI 0.03-0.82, P = 0.028) and fewer segments between LIV and LSTV (OR = 0.07, 95% CI 0.01-0.58, P = 0.013) were independent risk factors for the progression of the distal adding-on phenomenon. Lower skeletal maturity (Risser sign grade) and LIV located cephalad to LSTV are independent risk factors for the progression of the distal adding-on phenomenon in patients with Lenke type 1 and 2 AIS. For skeletally immature patients (Risser ≤ 3), LSTV should be preferentially chosen as LIV during surgery.

Scientific ReportsVol. 15(1)
Central South University (CN), The Central Hospital of Shaoyang (CN), Xiangya Hospital Central South University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Hunan Province
Openalex Percentile: Top 65%
Scoliosis diagnosis and treatment
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