Significance of interstitial cells of Cajal in Hirschsprung’s disease and intestinal neuronal dysplasia – A comparative study

Our findings suggest that there is a significant difference in the distribution of ICCs in the two muscular layers of HD and IND-B. Further multicenter studies are required to evaluate the utility of ICCs as a potential marker for differentiating HD from IND-B. Although nerve trunk thickness greater than 40 μ can be useful in differentiating HD from other non-motility disorders, it cannot be used to distinguish HD from IND-B.

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Publication Details

Journal
Indian Journal of Pathology and Microbiology
Published
2025-08-14
DOI
https://doi.org/10.4103/ijpm.ijpm_574_24
Primary Topic
Congenital gastrointestinal and neural anomalies
Type
article
Field-Weighted Citation Impact
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article

Significance of interstitial cells of Cajal in Hirschsprung’s disease and intestinal neuronal dysplasia – A comparative study

Shibsankar Barman, Suman K. Das, Uttara Chatterjee, Firdous Wasim Sk et al.
Indian Journal of Pathology and Microbiology
Congenital gastrointestinal and neural anomalies
article

Significance of interstitial cells of Cajal in Hirschsprung’s disease and intestinal neuronal dysplasia – A comparative study

Shibsankar Barman, Suman K. Das, Uttara Chatterjee, Firdous Wasim Sk, Aniket Halder, Ranajoy Ghosh, Ruchirendu Sarkar
article en

Abstract

Our findings suggest that there is a significant difference in the distribution of ICCs in the two muscular layers of HD and IND-B. Further multicenter studies are required to evaluate the utility of ICCs as a potential marker for differentiating HD from IND-B. Although nerve trunk thickness greater than 40 μ can be useful in differentiating HD from other non-motility disorders, it cannot be used to distinguish HD from IND-B.

Indian Journal of Pathology and MicrobiologyVol. 68(4)
Institute of Post Graduate Medical Education and Research (IN)
Openalex Percentile: Top 65%
Congenital gastrointestinal and neural anomalies
DOIOpen Access PDFOpenAlex
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Significance of interstitial cells of Cajal in Hirschsprung’s disease and intestinal neuronal dysplasia – A comparative study — Shibsankar Barman, Suman K. Das, et al. · Indian Journal of Pathology and Microbiology (2025) | TGRS Research Map | TGRS