Evolving genomic landscape of pediatric pneumococcus in two Canadian urban centers following conjugate vaccination
Our findings highlight sustained pneumococcal adaptation through serotype replacement, vaccine escape, and AMR dissemination. Ongoing genomic surveillance is essential to monitor these trends and inform vaccination policies.
Authors
- Allison McGeer (ORCID: https://orcid.org/0000-0001-5647-6137)
- Nahuel Fittipaldi (ORCID: https://orcid.org/0000-0001-9553-3798)
- James D. Kellner (ORCID: https://orcid.org/0000-0002-9083-2980)
- Agron Plevneshi
- Sarah Teatero (ORCID: https://orcid.org/0000-0003-1535-4947)
- Leah J. Ricketson (ORCID: https://orcid.org/0000-0003-1369-8391)
Institutions
- Alberta Health Services (CA)
- University of Calgary (CA)
- University of Toronto (CA)
- Alberta Children's Hospital (CA)
- Cegep de Saint Hyacinthe (CA)
- Public Health Ontario (CA)
- Sinai Health System (CA)
- Alberta Children's Hospital Research Institute
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-08-18
- DOI
- https://doi.org/10.3389/fmicb.2025.1642658
- Citations
- 1
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Joint Programming Initiative on Antimicrobial Resistance
- Canadian Institutes of Health Research