Unveiling the impact of bisphenol a exposure on gene expression and immune response in diabetic nephropathy through integrative toxicogenomics and molecular dynamics approaches
This study underscores the significant impact of BPA on gene expression and immune responses in DN. The identified key genes and their interactions with BPA provide valuable insights into the pathophysiological mechanisms of BPA-induced DN, paving the way for future research and potential therapeutic interventions.
Authors
- Yijun Dong (ORCID: https://orcid.org/0000-0002-2998-7035)
- Shan Lu (ORCID: https://orcid.org/0000-0002-8417-7588)
- Jin Shang (ORCID: https://orcid.org/0000-0003-2801-7683)
- Yan Zhang (ORCID: https://orcid.org/0000-0003-0680-5443)
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1186/s13098-025-01874-7
- Citations
- 1
- Primary Topic
- Effects and risks of endocrine disrupting chemicals
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- National Natural Science Foundation of China
- Zhengzhou University
- First Affiliated Hospital of Zhengzhou University