Primary central nervous system lymphomas in three “blue books” and correlation of recently defined primary large B-cell lymphoma of immune-privileged sites: Single-center experience

PCNSL is an extranodal non-Hodgkin lymphoma that typically affects older individuals and has a poor prognosis and challenging treatment. In this study, we re-evaluated our cases diagnosed with PCNSL using the three "blue books" and revised the diagnoses according to WHO HAEM5-Beta. The absence of MYC and BCL2 rearrangements supports the diagnosis of IP-LBCL, as determined by FISH analysis.

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Publication Details

Journal
Indian Journal of Pathology and Microbiology
Published
2025-08-14
DOI
https://doi.org/10.4103/ijpm.ijpm_401_24
Primary Topic
CNS Lymphoma Diagnosis and Treatment
Type
article
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article

Primary central nervous system lymphomas in three “blue books” and correlation of recently defined primary large B-cell lymphoma of immune-privileged sites: Single-center experience

İsmail Yılmaz, Ali Kaya, Ebru Zemheri, Irem Guvendir Bakkaloglu et al.
2 links
Indian Journal of Pathology and Microbiology
CNS Lymphoma Diagnosis and Treatment
article

Primary central nervous system lymphomas in three “blue books” and correlation of recently defined primary large B-cell lymphoma of immune-privileged sites: Single-center experience

İsmail Yılmaz, Ali Kaya, Ebru Zemheri, Irem Guvendir Bakkaloglu, Onur Şahin, Sabire Aslı Altunbas
article en

Abstract

PCNSL is an extranodal non-Hodgkin lymphoma that typically affects older individuals and has a poor prognosis and challenging treatment. In this study, we re-evaluated our cases diagnosed with PCNSL using the three "blue books" and revised the diagnoses according to WHO HAEM5-Beta. The absence of MYC and BCL2 rearrangements supports the diagnosis of IP-LBCL, as determined by FISH analysis.

Indian Journal of Pathology and MicrobiologyVol. 68(4)
Bahçeşehir University (TR), University of Health Science (KH), Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi (TR), Biruni University (TR), Ümraniye Eğitim ve Araştırma Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR), University of Health Sciences Antigua (AG)
Good health and well-being
Openalex Percentile: Top 69%
CNS Lymphoma Diagnosis and Treatment
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Primary central nervous system lymphomas in three “blue books” and correlation of recently defined primary large B-cell lymphoma of immune-privileged sites: Single-center experience — İsmail Yılmaz, Ali Kaya, et al. · Indian Journal of Pathology and Microbiology (2025) | TGRS Research Map | TGRS