Can Large Language Models Challenge CNNs in Medical Image Analysis?

This study presents a multimodal AI framework designed for precisely classifying medical diagnostic images. Utilizing publicly available datasets, the proposed system compares the strengths of convolutional neural networks (CNNs) and different large language models (LLMs). This in-depth comparative analysis highlights key differences in diagnostic performance, execution efficiency, and environmental impacts. Model evaluation was based on accuracy, F1-score, average execution time, average energy consumption, and estimated CO<inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> emission. The findings indicate that although CNN-based models can outperform various multimodal techniques that incorporate both images and contextual information, applying additional filtering on top of LLMs can lead to substantial performance gains. These findings highlight the transformative potential of multimodal AI systems to enhance the reliability, efficiency, and scalability of medical diagnostics in clinical settings.

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Publication Details

Published
2025-08-18
DOI
https://doi.org/10.1109/icip55913.2025.11084721
Citations
3
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
Field-Weighted Citation Impact
4.08
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article

Can Large Language Models Challenge CNNs in Medical Image Analysis?

Shahnewaz Karim Sakib, Shibbir Ahmed, Anindya Bijoy Das
3 citations
Radiomics and Machine Learning in Medical Imaging
4.08
article

Can Large Language Models Challenge CNNs in Medical Image Analysis?

Shahnewaz Karim Sakib, Shibbir Ahmed, Anindya Bijoy Das
article en
3 citations

Abstract

This study presents a multimodal AI framework designed for precisely classifying medical diagnostic images. Utilizing publicly available datasets, the proposed system compares the strengths of convolutional neural networks (CNNs) and different large language models (LLMs). This in-depth comparative analysis highlights key differences in diagnostic performance, execution efficiency, and environmental impacts. Model evaluation was based on accuracy, F1-score, average execution time, average energy consumption, and estimated CO<inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> emission. The findings indicate that although CNN-based models can outperform various multimodal techniques that incorporate both images and contextual information, applying additional filtering on top of LLMs can lead to substantial performance gains. These findings highlight the transformative potential of multimodal AI systems to enhance the reliability, efficiency, and scalability of medical diagnostics in clinical settings.

University of Akron (US), Texas State University (US), University of Tennessee at Chattanooga (US)
Openalex Percentile: Top 6%
Radiomics and Machine Learning in Medical Imaging
4.08
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Can Large Language Models Challenge CNNs in Medical Image Analysis? — Shahnewaz Karim Sakib, Shibbir Ahmed, et al. · (2025) | TGRS Research Map | TGRS