Tectorigenin could alleviate SA-AKI via reducing M1-like polarization of macrophages through KLF4/NF-κB pathway
Tectorigenin downregulates M1-like macrophage polarization through the KLF4/NF-κB pathway, reducing inflammation in renal tubular epithelial cells and alleviating SA-AKI.
Authors
- Guan Chen (ORCID: https://orcid.org/0000-0001-8834-039X)
- Yan Xu (ORCID: https://orcid.org/0000-0003-0261-8376)
- Wei Ding (ORCID: https://orcid.org/0000-0002-1421-0661)
- Wang Xiao-qian
- Wei Chunling
- Zhao Ruizhe
- Wang Liting
- Zhang Ningxin
- Xin Yanlu
- Song Zhuo
- Wu Xiaorui
- Gu Minghao
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1016/j.intimp.2025.115300
- Citations
- 2
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 1.61