Mixed germ cell tumor on an ectopic ovary with in a 9-year-old girl: A rare and complex case

Malignant ovarian germ cell tumors are rare in the pediatric population, particularly in children under ten years of age. We report a unique case of a mixed germ cell tumor, comprising dysgerminoma, mature and immature teratomas, and yolk sac tumor, located on an ectopic ovary, which was discovered following adnexal torsion in a 9-year-old girl with a family history of gynecological cancers. Mixed germ cell tumors present significant diagnostic challenges due to their heterogeneous histological composition and complex biological behavior. The patient's family history of gynecological cancers raises the possibility of an underlying genetic predisposition. This case underscores the importance of a comprehensive approach to pediatric pelvic masses, particularly in patients with a significant family history of cancer. Long-term follow-up is crucial for the early detection of recurrence in complex germ cell tumors.

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Publication Details

Journal
Radiology Case Reports
Published
2025-08-18
DOI
https://doi.org/10.1016/j.radcr.2025.07.047
Primary Topic
Testicular diseases and treatments
Type
article
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Mixed germ cell tumor on an ectopic ovary with in a 9-year-old girl: A rare and complex case

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Mixed germ cell tumor on an ectopic ovary with in a 9-year-old girl: A rare and complex case

Siham El Haddad, Lina Belkouchi, Chaimae Abourak, Jaouad Bouljrouf, Mounir Kisra, Latifa Chat, Nazik Allali, Oukassem Siham, Wadie Zouita, Imade Bougrine
article en

Abstract

Malignant ovarian germ cell tumors are rare in the pediatric population, particularly in children under ten years of age. We report a unique case of a mixed germ cell tumor, comprising dysgerminoma, mature and immature teratomas, and yolk sac tumor, located on an ectopic ovary, which was discovered following adnexal torsion in a 9-year-old girl with a family history of gynecological cancers. Mixed germ cell tumors present significant diagnostic challenges due to their heterogeneous histological composition and complex biological behavior. The patient's family history of gynecological cancers raises the possibility of an underlying genetic predisposition. This case underscores the importance of a comprehensive approach to pediatric pelvic masses, particularly in patients with a significant family history of cancer. Long-term follow-up is crucial for the early detection of recurrence in complex germ cell tumors.

Radiology Case ReportsVol. 20(11)
Mohammed V University (MA), Ibn Sina Hospital (KW)
Zero hunger, Gender equality
Openalex Percentile: Top 66%
Testicular diseases and treatments
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