Clinical Outcomes of Ezetimibe Plus Statins in Patients With Lower Extremity Artery Disease
Compared to statin monotherapy, an intensified lipid-lowering strategy (ie, ezetimibe plus statins), significantly reduced the incidence of major lower limb amputation and all-cause mortality in real-world patients with LEAD.
Authors
- Atsuyuki Wada (ORCID: https://orcid.org/0000-0002-0877-4436)
- Takefumi Kishimori (ORCID: https://orcid.org/0009-0000-9639-5470)
- Takafumi Yagi
- Jumpei Koike
- Masaharu Okada
- Takehiro Matsumoto (ORCID: https://orcid.org/0000-0002-0379-5334)
- Takenobu Shimada (ORCID: https://orcid.org/0000-0002-6300-9112)
- Yoshihiro Iwasaki
Institutions
- Kansai Medical University (JP)
- Omron (Japan) (JP)
- Osaka Metropolitan University (JP)
- Tokyo Metropolitan University (JP)
Publication Details
- Journal
- JACC Advances
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1016/j.jacadv.2025.102074
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00