Live birth outcomes after euploid transfer: autologous vs. donor oocyte embryos in patients aged > 35 years

Increasing maternal age decreases the likelihood of live birth for autologous euploid embryo transfers; however, the likelihood of live birth did not change with increasing maternal age among patients using donor oocyte-derived euploid embryos. This suggests that oocyte quality depends not only on ploidy status but also on age-related ooplasmic factors.

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Publication Details

Journal
F&S Reports
Published
2025-08-18
DOI
https://doi.org/10.1016/j.xfre.2025.08.006
Primary Topic
Prenatal Screening and Diagnostics
Type
article
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article

Live birth outcomes after euploid transfer: autologous vs. donor oocyte embryos in patients aged > 35 years

Michael Homer, Luis R. Hoyos, Micah J. Hill, Phillip A. Romanski et al.
1 links
F&S Reports
Prenatal Screening and Diagnostics
article

Live birth outcomes after euploid transfer: autologous vs. donor oocyte embryos in patients aged > 35 years

Michael Homer, Luis R. Hoyos, Micah J. Hill, Phillip A. Romanski, Howard J. Li, Kerry S.J. Flannagan, Kate Devine, Peter G. Lindner, Chunhui Wang, Meike L. Uhler
article en

Abstract

Increasing maternal age decreases the likelihood of live birth for autologous euploid embryo transfers; however, the likelihood of live birth did not change with increasing maternal age among patients using donor oocyte-derived euploid embryos. This suggests that oocyte quality depends not only on ploidy status but also on age-related ooplasmic factors.

F&S ReportsVol. 6(4)
National Institutes of Health (US), Walter Reed National Military Medical Center (US), Reproductive Science Center (US), Fertility Centers of Illinois (US), Reproductive Medicine Associates of New York (US), Eunice Kennedy Shriver National Institute of Child Health and Human Development (US), Reproductive Biology Associates (US), Shady Grove Fertility Center (US)
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Openalex Percentile: Top 70%
Prenatal Screening and Diagnostics
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