Dedifferentiated liposarcoma with low-grade fibromyxoid sarcoma and inflammatory myofibroblastic tumor: A case report and literature review

This case underscores critical clinical lessons: diagnostic vigilance is paramount when assessing sarcomas with mixed morphological patterns, given that DDLPS may closely mimic IMT or LGFMS. To prevent misdiagnosis, a systematic diagnostic approach radiological, immunohistochemistry, and confirmatory molecular testing is essential. Therapeutic management relies on complete surgical resection, with adjuvant therapy decisions guided by multidisciplinary evaluation. Long-term surveillance remains necessary due to recognized risks of late recurrence in retroperitoneal DDLPS, mandating sustained follow-up.

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Publication Details

Journal
Medicine
Published
2025-08-15
DOI
https://doi.org/10.1097/md.0000000000043806
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Dedifferentiated liposarcoma with low-grade fibromyxoid sarcoma and inflammatory myofibroblastic tumor: A case report and literature review

Yuzhen Huang, Lixia Zeng, Xiaoyu Chen, Yun Ma et al.
Medicine
Sarcoma Diagnosis and Treatment
article

Dedifferentiated liposarcoma with low-grade fibromyxoid sarcoma and inflammatory myofibroblastic tumor: A case report and literature review

Yuzhen Huang, Lixia Zeng, Xiaoyu Chen, Yun Ma, Jing Huang
article en

Abstract

This case underscores critical clinical lessons: diagnostic vigilance is paramount when assessing sarcomas with mixed morphological patterns, given that DDLPS may closely mimic IMT or LGFMS. To prevent misdiagnosis, a systematic diagnostic approach radiological, immunohistochemistry, and confirmatory molecular testing is essential. Therapeutic management relies on complete surgical resection, with adjuvant therapy decisions guided by multidisciplinary evaluation. Long-term surveillance remains necessary due to recognized risks of late recurrence in retroperitoneal DDLPS, mandating sustained follow-up.

MedicineVol. 104(33)
Guangxi Medical University (CN)
Openalex Percentile: Top 68%
Sarcoma Diagnosis and Treatment
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Dedifferentiated liposarcoma with low-grade fibromyxoid sarcoma and inflammatory myofibroblastic tumor: A case report and literature review — Yuzhen Huang, Lixia Zeng, et al. · Medicine (2025) | TGRS Research Map | TGRS