Nephrotic syndrome associated with Guillain–Barré syndrome and Sjögren syndrome: A case report and literature review

This case illustrates the rare coexistence of GBS, MCD, and Sjögren syndrome kidney injury in a single patient. Autoimmune markers played a pivotal role in the pathogenesis of these diseases. Immunosuppressive therapy and intravenous immunoglobulin were essential in treating both neurological and renal complications. Further research is needed to deepen our understanding of the overlap of autoimmune diseases and to optimize treatment strategies for such complex cases.

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Publication Details

Journal
Medicine
Published
2025-08-15
DOI
https://doi.org/10.1097/md.0000000000043824
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Nephrotic syndrome associated with Guillain–Barré syndrome and Sjögren syndrome: A case report and literature review

Ping Guo, Ying Wang, Wei Wang, Ping Zhang et al.
Medicine
Peripheral Neuropathies and Disorders
article

Nephrotic syndrome associated with Guillain–Barré syndrome and Sjögren syndrome: A case report and literature review

Ping Guo, Ying Wang, Wei Wang, Ping Zhang, Jia Zhao
article en

Abstract

This case illustrates the rare coexistence of GBS, MCD, and Sjögren syndrome kidney injury in a single patient. Autoimmune markers played a pivotal role in the pathogenesis of these diseases. Immunosuppressive therapy and intravenous immunoglobulin were essential in treating both neurological and renal complications. Further research is needed to deepen our understanding of the overlap of autoimmune diseases and to optimize treatment strategies for such complex cases.

MedicineVol. 104(33)
Bond University (AU), The University of Sydney (AU), University of Electronic Science and Technology of China (CN), Concord Repatriation General Hospital (AU), The George Institute for Global Health (AU), Macquarie University (AU)
Openalex Percentile: Top 69%
Peripheral Neuropathies and Disorders
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