Skin perfusion pressure, distal blood pressure vs. trans cutaneous oxygen pressure for predicting wound healing after major amputation
We found poor (71%-74%) crude agreement between SPP and TcPO<sub>2</sub>, concerning measurements above and below the knee, using the established diagnostic cut-offs for predicting a high probability of postamputation wound healing. We determined that SPP and TcPO<sub>2</sub> evaluate different physiological properties of the microcirculation and cannot be interchanged. Additionally, we found that the actual amputation level is often chosen at another level than that suggested by SPP and TcPO<sub>2</sub>, indicating that the choice is based on a multitude of factors, including clinical, paraclinical and patient-related parameters.
Authors
- Annette Høgh (ORCID: https://orcid.org/0000-0001-7525-9007)
- Jens Peder Dreyer Paludan (ORCID: https://orcid.org/0000-0002-1699-4500)
- Christian Høyer (ORCID: https://orcid.org/0000-0003-0491-1680)
- Helle Damgaard Zacho (ORCID: https://orcid.org/0000-0001-9089-288X)
Institutions
- Aalborg University Hospital (DK)
- Regionshospitalet Viborg (DK)
- Aalborg University (DK)
Publication Details
- Journal
- Clinical Physiology and Functional Imaging
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1111/cpf.70025
- Citations
- 1
- Primary Topic
- Diabetic Foot Ulcer Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.29