Identification of neoantigen epitopes in cervical cancer by multi-omics analysis
Our analysis highlights the potential of PCLO as a candidate gene for enhancing immune cell infiltration and activating immune responses in tumors. The peptides SISRFTLEK (PCLO<sup>L4169F</sup>) and LSEAGHFFY (PCLO<sup>A3000S</sup>) are promising targets for tumor vaccines.
Authors
- Jing Yuan (ORCID: https://orcid.org/0000-0002-3844-5502)
- Xiaohua Gong (ORCID: https://orcid.org/0000-0003-2074-1802)
- Kezhen Li (ORCID: https://orcid.org/0000-0001-7943-5389)
- Yingyan Han
- Jihui Ai (ORCID: https://orcid.org/0000-0002-1743-2980)
- Na Xu (ORCID: https://orcid.org/0000-0001-9457-2293)
Institutions
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1186/s40001-025-03036-x
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China