Microneedling-assisted delivery of metformin versus tranexamic acid in treating melasma: a randomized controlled study

Microneedling with topical TXA demonstrated superior efficacy and patient satisfaction compared to metformin and Kligman's formula. While topical metformin showed some potential, its formulation and clinical utility require further study. Microneedling offers a promising approach to improve treatment outcomes in melisma.

Authors

Institutions

Publication Details

Journal
European journal of medical research
Published
2025-08-18
DOI
https://doi.org/10.1186/s40001-025-03032-1
Citations
3
Primary Topic
Dermatologic Treatments and Research
Type
article
Field-Weighted Citation Impact
6.01

Funders

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article

Microneedling-assisted delivery of metformin versus tranexamic acid in treating melasma: a randomized controlled study

Ahmed S. Kadah, Mohamed L. Elsaie, Mohamed Mahran, Abdelshakour Al Mohammady
3 citations
European journal of medical research
Dermatologic Treatments and Research
6.01
article

Microneedling-assisted delivery of metformin versus tranexamic acid in treating melasma: a randomized controlled study

Ahmed S. Kadah, Mohamed L. Elsaie, Mohamed Mahran, Abdelshakour Al Mohammady
article en
3 citations

Abstract

Microneedling with topical TXA demonstrated superior efficacy and patient satisfaction compared to metformin and Kligman's formula. While topical metformin showed some potential, its formulation and clinical utility require further study. Microneedling offers a promising approach to improve treatment outcomes in melisma.

European journal of medical researchVol. 30(1)
Al-Azhar University (EG), National Research Centre (EG), Al Azhar University (QA)
Science and Technology Development Fund
Openalex Percentile: Top 4%
Dermatologic Treatments and Research
6.01
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