A Decade of Prenatal Genetic Diagnostics: Insights From 1949 Cases at a Medical Genetics Facility in South India
This study reiterates the safety of prenatal diagnostic procedures when performed by skilled personnel following standard protocols, even in low-resource settings. Monogenic disorders are the commonest test indication and the predominant cause of ultrasound abnormalities, reflecting the high burden of autosomal recessive disorders in our cohort.
Authors
- Angalena Ramachandran
- Prajnya Ranganath (ORCID: https://orcid.org/0000-0001-7122-3197)
- Ashwin Bhikaji Dalal (ORCID: https://orcid.org/0000-0001-5929-745X)
- Usha R. Dutta (ORCID: https://orcid.org/0000-0003-1491-5212)
- Shagun Aggarwal (ORCID: https://orcid.org/0000-0001-8738-9888)
- Rajitha Ponnala
- Balasubramanian Raman (ORCID: https://orcid.org/0000-0001-6277-6267)
- Vasantha Rani Sarvade
- J. P. Jain
- Javeria Nisar
- Sahithi Rathod Ramavath
- Muthulakshmi Mayandi
- Prathyusha Koneru (ORCID: https://orcid.org/0000-0002-7359-3009)
- Harika Patnaik Chinchilam
Institutions
- Nizam's Institute of Medical Sciences (IN)
- Centre for DNA Fingerprinting and Diagnostics (IN)
Publication Details
- Journal
- Prenatal Diagnosis
- Published
- 2025-08-16
- DOI
- https://doi.org/10.1002/pd.6869
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00