Human Papillomavirus Type and Viral Load in Relation to Circulating Cell-Free Tumour HPV DNA Level and Survival in Cervical Cancer
Cell-free tumour HPV DNA, HPV type and viral load are promising biomarkers in cervical cancer. The lower sensitivity for ctHPV DNA detection for alpha-7 species, including HPV18, needs to be considered in future studies on ctHPV DNA, especially if used as a marker for relapse during surveillance when ctHPV DNA levels are very low.
Authors
- Emma Tham (ORCID: https://orcid.org/0000-0001-6079-164X)
- Kristina Hellman (ORCID: https://orcid.org/0000-0002-5124-7412)
- Lars Sivars (ORCID: https://orcid.org/0000-0001-7272-3599)
- Cecilia Jylhä (ORCID: https://orcid.org/0000-0002-6964-2517)
- Mark Zupancic (ORCID: https://orcid.org/0000-0003-4013-7688)
Institutions
- Uppsala University (SE)
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
Publication Details
- Journal
- Molecular Diagnosis & Therapy
- Published
- 2025-08-16
- DOI
- https://doi.org/10.1007/s40291-025-00809-2
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cancerfonden
- Karolinska Institutet
- Magnus Bergvalls Stiftelse
- Uppsala Universitet
- Landstinget i Uppsala län
- Region Uppsala