Differential regulation of FADS2 by EZH2 reveals a metabolic vulnerability in ovarian cancer treatment
This work was supported by the Youth Program of the National Natural Science Foundation of China (No. 82203102, No. 82303801, No. 82203433), the National Key Research and Development Program of China (2022YFA1104001), the General Program of the National Natural Science Foundation of China (No. 82272745, No. 82072870, No. 81972966, No. 82373173, No. 82073057), and the Peking University Third Hospital Clinical Key Project (BYSY2022069, BYSY2022070, BYSYZD2023010).
Authors
- Lixiang Xue (ORCID: https://orcid.org/0000-0003-1507-7193)
- Zhengyang Guo (ORCID: https://orcid.org/0009-0004-0363-6765)
- Yinjia Li
- Celina G. Kleer (ORCID: https://orcid.org/0000-0001-8195-185X)
- Li‐Jun Ma (ORCID: https://orcid.org/0000-0002-2733-3708)
- Ying Song (ORCID: https://orcid.org/0000-0002-2300-0324)
- Tong Liu (ORCID: https://orcid.org/0000-0002-9111-0226)
- Yuqing Wang (ORCID: https://orcid.org/0009-0006-2028-8138)
- Jiagui Song (ORCID: https://orcid.org/0000-0001-9741-0652)
- Yang Bai
- Jianling Yang
- Xiao Huo (ORCID: https://orcid.org/0000-0002-1158-2136)
Institutions
- Peking University (CN)
- University of Michigan (US)
- Peking University Cancer Hospital (CN)
- Ningxia Medical University (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- EBioMedicine
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1016/j.ebiom.2025.105879
- Citations
- 1
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China
- Peking University
- Peking University Third Hospital
- National Key Research and Development Program of China