Growth Patterns in Shwachman-Diamond Syndrome: Findings from the North American Shwachman-Diamond Syndrome Registry
This study of SDS across a diverse North American sample extends available growth data for this rare condition, confirming persistent short stature but normal BMI for age in SDS. HSCT was associated with a reduction in growth. No significant change in height velocity was observed with GH therapy. These data will inform clinical growth evaluation in SDS patients.
Authors
- Kasiani C. Myers (ORCID: https://orcid.org/0000-0002-5528-4405)
- Claire Dusa
- Diana Schwarz
- Sara Loveless
- Lindsey Hornung (ORCID: https://orcid.org/0000-0003-0722-7307)
- Jane Koo (ORCID: https://orcid.org/0000-0003-1858-2881)
- Sarah K. Steltz
- Elizabeth Korn
- L Schwarz
- Leah Cheng
- Akiko Shimamura
- Jonathan C. Howell (ORCID: https://orcid.org/0000-0002-3948-532X)
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Boston Children's Hospital (US)
- Boston Children's Museum (US)
- Dana-Farber/Boston Children's Cancer and Blood Disorders Center (US)
Publication Details
- Journal
- The Journal of Pediatrics
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1016/j.jpeds.2025.114780
- Primary Topic
- Blood disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00