Phosphorylation of Pyruvate Dehydrogenase as a Marker of Neuronal Inactivity in the Enteric Nervous System
This study establishes pPDH as a robust marker for neuronal inactivation in the ENS, complementing existing activation markers like pERK. These findings provide a novel framework for exploring neuron-glia communication and neuronal dynamics in the gut.
Authors
- Brian D. Gulbransen (ORCID: https://orcid.org/0000-0003-1145-3227)
- Jonathon L. McClain
- Eve Wemelle
Institutions
- Michigan State University (US)
Publication Details
- Journal
- Neurogastroenterology & Motility
- Published
- 2025-08-16
- DOI
- https://doi.org/10.1111/nmo.70135
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of Diabetes and Digestive and Kidney Diseases