SOX9 Is a Key Factor for the Postnatal Maturation of the Intrahepatic Bile Duct Network
These findings underscore the pivotal role of SOX9 in postnatal bile duct network development, demonstrating its critical involvement in maintaining structural organization. The results suggest that SOX9 plays a more substantial role in bile duct maturation than previously recognized, providing new insights into its regulatory mechanisms in liver development.
Authors
- Yukio Fujiwara (ORCID: https://orcid.org/0000-0002-2074-0597)
- Hiroki Hirao (ORCID: https://orcid.org/0000-0002-1546-2676)
- Shigeyuki Esumi
- Masaki Honda (ORCID: https://orcid.org/0000-0001-5526-2591)
- Taizo Hibi (ORCID: https://orcid.org/0000-0002-6867-228X)
- Daiki Yoshii (ORCID: https://orcid.org/0000-0003-2519-7711)
- Yoshihiro Komohara (ORCID: https://orcid.org/0000-0001-9723-0846)
- Ahmad Adawy (ORCID: https://orcid.org/0000-0003-3572-0123)
- Yuji Yokouchi
Institutions
- Mansoura University (EG)
- Kumamoto University Hospital (JP)
- Kumamoto University (JP)
Publication Details
- Journal
- Hepatology Research
- Published
- 2025-08-16
- DOI
- https://doi.org/10.1111/hepr.70012
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education, Culture, Sports, Science and Technology
- Forskningsrådet om Hälsa, Arbetsliv och Välfärd
- Japan Society for the Promotion of Science