Data-driven cognitive subtypes in major depressive disorder: Grey matter atrophy in the left fusiform gyrus and cerebellum

A subtype of MDD characterized by comprehensive cognitive deficits is associated with structural atrophy in the left fusiform gyrus and cerebellum, suggesting these regions as potential biomarkers for the cognitive deficit subtype of MDD. However, no significant differences in ALFF were observed between the two cognitive subgroups.

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Publication Details

Journal
Journal of Affective Disorders
Published
2025-08-15
DOI
https://doi.org/10.1016/j.jad.2025.120068
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Data-driven cognitive subtypes in major depressive disorder: Grey matter atrophy in the left fusiform gyrus and cerebellum

Huanhuan Fan, Yushun Yan, Rong‐Jun Ni, Xiaohong Ma et al.
Journal of Affective Disorders
Functional Brain Connectivity Studies
article

Data-driven cognitive subtypes in major depressive disorder: Grey matter atrophy in the left fusiform gyrus and cerebellum

Huanhuan Fan, Yushun Yan, Rong‐Jun Ni, Xiaohong Ma, Min Wang, Xiao Yang, Liansheng Zhao, Jinxue Wei, Yikai Dou, Yuanmei Tao
article en

Abstract

A subtype of MDD characterized by comprehensive cognitive deficits is associated with structural atrophy in the left fusiform gyrus and cerebellum, suggesting these regions as potential biomarkers for the cognitive deficit subtype of MDD. However, no significant differences in ALFF were observed between the two cognitive subgroups.

Journal of Affective DisordersVol. 391
Sichuan University (CN), West China Hospital of Sichuan University (CN)
Reduced inequalities
Openalex Percentile: Top 79%
Functional Brain Connectivity Studies
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Data-driven cognitive subtypes in major depressive disorder: Grey matter atrophy in the left fusiform gyrus and cerebellum — Huanhuan Fan, Yushun Yan, et al. · Journal of Affective Disorders (2025) | TGRS Research Map | TGRS