Rethinking the role of bisphosphonates after denosumab treatment in locally advanced or unresectable aneurysmal bone cysts: A meta-analysis

BPs used in post-denosumab ossifying ABCs appear to improve treatment outcomes, presumably by targeting residual tumor cells. Prospective clinical studies are warranted to validate this promising two-stage conceptual strategy in difficult-to-treat ABC.

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Publication Details

Journal
World Journal of Orthopedics
Published
2025-08-08
DOI
https://doi.org/10.5312/wjo.v16.i8.107083
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
Field-Weighted Citation Impact
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article

Rethinking the role of bisphosphonates after denosumab treatment in locally advanced or unresectable aneurysmal bone cysts: A meta-analysis

Gennady N. Machak, Øyvind S. Bruland, Kovalev Av, С. С. Родионова
World Journal of Orthopedics
Bone Tumor Diagnosis and Treatments
article

Rethinking the role of bisphosphonates after denosumab treatment in locally advanced or unresectable aneurysmal bone cysts: A meta-analysis

Gennady N. Machak, Øyvind S. Bruland, Kovalev Av, С. С. Родионова
article en

Abstract

BPs used in post-denosumab ossifying ABCs appear to improve treatment outcomes, presumably by targeting residual tumor cells. Prospective clinical studies are warranted to validate this promising two-stage conceptual strategy in difficult-to-treat ABC.

World Journal of OrthopedicsVol. 16(8)
Oslo University Hospital (NO), Norwegian Cancer Society (NO), Central Scientific Research Institute of Traumatology and Orthopedics (RU), National Medical Research Center of Cardiology (RU)
Good health and well-being
Openalex Percentile: Top 68%
Bone Tumor Diagnosis and Treatments
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