Electroacupuncture ameliorates visceral hypersensitivity and negative emotions by regulating paraventricular hypothalamic nucleus and colonic corticotropin-releasing factor signaling
This research highlights the key role of PVN CRF-MC CRF-R1 and the downstream MC/TRPV1 pathway in the pathological process of IBS-D and the mechanism of the effect of EA.
Authors
- Guo-Ming Shen (ORCID: https://orcid.org/0000-0002-5983-0370)
- Shun Hsien Huang (ORCID: https://orcid.org/0009-0003-3954-024X)
- Tianxiao Li (ORCID: https://orcid.org/0000-0003-3585-5001)
- Xiyang Wang (ORCID: https://orcid.org/0000-0002-8492-9129)
- Shengting Zhu
- Hao Wang (ORCID: https://orcid.org/0000-0003-4082-9350)
- Hongkun Ma
- Jiangang Xu (ORCID: https://orcid.org/0000-0003-2244-8423)
- Yi Yuan (ORCID: https://orcid.org/0009-0009-4128-0444)
Institutions
- Anhui Medical University (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- National Science Centre (PL)
Publication Details
- Journal
- World Journal of Psychiatry
- Published
- 2025-08-08
- DOI
- https://doi.org/10.5498/wjp.v15.i8.107342
- Citations
- 1
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.81