Clinicopathological Challenge: A Progressively Enlarging Hardened Skin Plaque
Stiff skin syndrome (SSS) is a rare connective tissue disease manifesting as a progressive, non-inflammatory fibrosis that causes the skin and soft tissues to harden. It can result in restricted joint movement, particularly affecting the shoulder and pelvic girdle. A segmental variant with a better prognosis has been described. Due to its similarity in presentation to other scleroderma-like conditions, this case report will discuss it as a diagnostic challenge.
Authors
- Rodrigo Roldán–Marín (ORCID: https://orcid.org/0000-0002-6832-5915)
- Sonia Toussaint‐Caire (ORCID: https://orcid.org/0000-0002-6883-3100)
- Marian Fernández-Martínez (ORCID: https://orcid.org/0009-0007-4872-6846)
- Frida Paola Rivera Lira
Institutions
- Centro Médico Nacional La Raza (MX)
- Hospital General Dr. Manuel Gea Gonzalez (MX)
- University Dermatology (US)
- Sanofi (Mexico) (MX)
Publication Details
- Journal
- International Journal of Dermatology
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1111/ijd.70022
- Primary Topic
- Dermatological and Skeletal Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00