Metabolomic insights into vitreous humor with therapy outcome in type 2 diabetic retinopathy
This study highlights the potential of Dodecanoylcarnitine, Linoleylcarnitine, Stearylcarnitine, Decanoic acid, and Proline as biomarkers for predicting therapeutic outcomes following vitrectomy for T2DR. These findings provide novel insights into the metabolic factors influencing treatment response variability and suggest pathways for future therapeutic interventions.
Authors
- Yanyan Hao (ORCID: https://orcid.org/0009-0009-7083-1444)
- Gongyu Huang
- Jiwei Tao
- Zhe Lv (ORCID: https://orcid.org/0000-0001-8660-7767)
- Yun Zhang (ORCID: https://orcid.org/0000-0002-8612-6880)
- Xuyang Chu (ORCID: https://orcid.org/0000-0002-4674-0499)
- Shixin Zhao (ORCID: https://orcid.org/0000-0002-9974-8160)
- Xiangjun She
Institutions
- Wenzhou Medical University (CN)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
Publication Details
- Journal
- BMC Ophthalmology
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1186/s12886-025-04283-6
- Citations
- 1
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province