Balz–Schiemann-Type Oxidative C(sp<sup>3</sup>)–H Fluorination of Alkanes and Alkylarenes
<i>N</i>-Aroyloxyquinuclidinium tetrafluoroborates allow for efficient Balz-Schiemann-type oxidative C-H fluorination of donors of 1°, 2° and 3° benzylic C-H bonds used as limiting reagents under photocatalytic conditions; cyclohexane was also shown to react, albeit less efficiently.
Authors
- Michael Hitt (ORCID: https://orcid.org/0000-0002-8950-148X)
- Andrei N. Vedernikov (ORCID: https://orcid.org/0000-0002-7371-793X)
- Prahadeesh Nagaretnam
Institutions
- University of Maryland, College Park (US)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1021/acs.orglett.5c02886
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Defense
- University of Maryland
- Division of Chemistry