Deciphering the methylation landscape of long noncoding RNAs in hepatocellular carcinoma: a focus on LINC00942
A substantial quantity of lncRNAs is transcriptionally modulated by methylation in HCC. The demethylation of LINC00942 within its promoter region facilitates the upregulation of LINC00942 expression, thereby contributing to its function as an oncogene in HCC.
Authors
- Duguang Li
- Hui Lin (ORCID: https://orcid.org/0000-0001-5459-800X)
- Zhaoqi Shi
- Xiaolong Liu (ORCID: https://orcid.org/0000-0003-1236-1332)
- Jing Yang (ORCID: https://orcid.org/0000-0001-5579-1119)
- Haonan Chen (ORCID: https://orcid.org/0000-0001-8885-5051)
- Xiaoxiao Fan
Institutions
- Sir Run Run Shaw Hospital (CN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1186/s13148-025-01952-7
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- Fundamental Research Funds for the Central Universities
- Natural Science Foundation of Zhejiang Province