Distinguishing Reactive Lymphocytes From Blasts Using Fractal Chromatin Patterns

Our results suggest that a classification algorithm can effectively distinguish between blasts and RLs based solely on fractal chromatin patterns. It is possible that a similar algorithm could be utilized in the clinical hematology laboratory to assist in distinguishing RLs and blasts in peripheral blood smears.

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Publication Details

Journal
International Journal of Laboratory Hematology
Published
2025-08-16
DOI
https://doi.org/10.1111/ijlh.14541
Primary Topic
Digital Imaging for Blood Diseases
Type
article
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article

Distinguishing Reactive Lymphocytes From Blasts Using Fractal Chromatin Patterns

Ryan Cordner, Abigail Gordhamer, Henry Tullis
International Journal of Laboratory Hematology
Digital Imaging for Blood Diseases
article

Distinguishing Reactive Lymphocytes From Blasts Using Fractal Chromatin Patterns

Ryan Cordner, Abigail Gordhamer, Henry Tullis
article en

Abstract

Our results suggest that a classification algorithm can effectively distinguish between blasts and RLs based solely on fractal chromatin patterns. It is possible that a similar algorithm could be utilized in the clinical hematology laboratory to assist in distinguishing RLs and blasts in peripheral blood smears.

International Journal of Laboratory HematologyVol. 47(6)
Brigham Young University (US)
Life in Land
Openalex Percentile: Top 80%
Digital Imaging for Blood Diseases
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Distinguishing Reactive Lymphocytes From Blasts Using Fractal Chromatin Patterns — Ryan Cordner, Abigail Gordhamer, et al. · International Journal of Laboratory Hematology (2025) | TGRS Research Map | TGRS