Molecular epidemiology, antimicrobial resistance, and virulence characteristics of predominant methicillin-resistant Staphylococcus aureus clones with strong biofilm-producing capability from a tertiary teaching hospital in China

This is the first report of the phenotypic-genotypic characteristics of MRSA with both strong biofilm-producing and virulence potential, with ST5-t2460, ST59-t437, and ST239-t030 clones accounting for the major genotypes. Further exploration of specific virulence genes correlating to the pathogenesis of this superbug is deemed essential for developing targeted infection control and treatment strategies in the future.

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Publication Details

Journal
BMC Microbiology
Published
2025-08-15
DOI
https://doi.org/10.1186/s12866-025-04258-z
Primary Topic
Antimicrobial Resistance in Staphylococcus
Type
article
Field-Weighted Citation Impact
0.00

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article

Molecular epidemiology, antimicrobial resistance, and virulence characteristics of predominant methicillin-resistant Staphylococcus aureus clones with strong biofilm-producing capability from a tertiary teaching hospital in China

Junrui Wang, Mingju Hao
BMC Microbiology
Antimicrobial Resistance in Staphylococcus
article

Molecular epidemiology, antimicrobial resistance, and virulence characteristics of predominant methicillin-resistant Staphylococcus aureus clones with strong biofilm-producing capability from a tertiary teaching hospital in China

Junrui Wang, Mingju Hao
article en

Abstract

This is the first report of the phenotypic-genotypic characteristics of MRSA with both strong biofilm-producing and virulence potential, with ST5-t2460, ST59-t437, and ST239-t030 clones accounting for the major genotypes. Further exploration of specific virulence genes correlating to the pathogenesis of this superbug is deemed essential for developing targeted infection control and treatment strategies in the future.

BMC MicrobiologyVol. 25(1)
Inner Mongolia Medical University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 74%
Antimicrobial Resistance in Staphylococcus
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