Pediatric-Onset Polyarteritis Nodosa and Deficiency of Adenosine Deaminase 2
Anti-TNF therapy remains the mainstay of treatment in DADA2 and is effective in preventing disease progression. In contrast, classic sPAN may require escalation to biologic agents in refractory cases or when neurologic or end-organ involvement is present.
Authors
- Betül Sözeri (ORCID: https://orcid.org/0000-0002-5079-5644)
- Sıla Atamyıldız Uçar (ORCID: https://orcid.org/0000-0002-4283-0921)
- Şeyma Türkmen (ORCID: https://orcid.org/0000-0002-2318-0361)
- Eray Tunce (ORCID: https://orcid.org/0000-0002-4801-6605)
- Metin Eser (ORCID: https://orcid.org/0000-0001-7118-7958)
Institutions
- Ümraniye Eğitim ve Araştırma Hastanesi (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- Center for Rheumatology (US)
Publication Details
- Journal
- JCR Journal of Clinical Rheumatology
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1097/rhu.0000000000002270
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00