m6A-modified circZNF548 regulates exosomal miR-7108-3p to activate CD3+CD8+ T cells and suppress NSCLC growth by JMY
m6A-modified circZNF548 suppresses NSCLC cell proliferation and migration by enhancing anti-tumor immunity via exosomal miR-7108-3p and the JMY-p53 pathway. These findings suggest new therapeutic targets for NSCLC.
Authors
- D. S. Cao
- Youjie Li (ORCID: https://orcid.org/0000-0001-9296-0903)
- Yu-Long Zhao
- Yan Liang (ORCID: https://orcid.org/0000-0003-4145-3463)
- Qin Wang (ORCID: https://orcid.org/0000-0002-9202-8005)
- Jiangnan Xue
- Yang Guo
- Yanmei Li (ORCID: https://orcid.org/0000-0002-3531-5067)
- Ning Xie (ORCID: https://orcid.org/0000-0002-4628-2299)
- Hongfang Sun
- Xiyan Li (ORCID: https://orcid.org/0000-0002-1959-2160)
- Ping Yu Wang
- Chunxia Wu (ORCID: https://orcid.org/0000-0001-5653-3824)
- Shu-Yang Xie
- Xiaohua Li (ORCID: https://orcid.org/0000-0001-5183-8055)
Institutions
- Binzhou Medical University (CN)
- Shandong University of Aeronautics (CN)
- Yantaishan Hospital (CN)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1186/s12915-025-02355-z
- Citations
- 4
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- National Natural Science Foundation of China