Podocyte Proteomics Revealed hUCMSC-Exosomes Ameliorate Diabetic Kidney Disease through Inhibiting Talin-1 Mediated EMT
This study highlights the potential of hUCMSC-derived exosomes as a therapeutic strategy for DKD by ameliorating Talin-1-mediated podocyte EMT.
Authors
- Xuechun Yang (ORCID: https://orcid.org/0000-0003-4858-2743)
- Cong-min Tang
- Yanqiu Xing (ORCID: https://orcid.org/0000-0003-0441-8562)
- Junchao Feng
- Tonghui Ma (ORCID: https://orcid.org/0000-0001-9338-1030)
- J. H. Zou (ORCID: https://orcid.org/0000-0003-3581-2829)
- Mingying Ling
- Zhen Zhang (ORCID: https://orcid.org/0000-0001-6286-8049)
- Xuehui Li (ORCID: https://orcid.org/0000-0002-9644-2422)
- Na Yu (ORCID: https://orcid.org/0000-0003-1818-2562)
- Yiping Song
- Wenjing Ding
- Chuanli Zhao
- Wenzhuo Yu
- Di Liu (ORCID: https://orcid.org/0009-0008-1512-5662)
Institutions
- Statistics New Zealand (NZ)
- Capital University (US)
- Capital Medical University (CN)
- Institute of Physiology and Basic Medicine (RU)
- Health Outcomes Solutions (United States) (US)
- The People's Hospital Tongling (CN)
- Cell Technology (China) (HK)
- Kai Biotech (South Korea) (KR)
- Institute of Aging (CA)
- Center for Clinical Research (United States) (US)
- Beijing Shijitan Hospital (CN)
- Shanghai Cell Therapy Research Institute (CN)
- Qilu Hospital of Shandong University (CN)
- Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
Publication Details
- Journal
- Journal of Proteome Research
- Published
- 2025-08-16
- DOI
- https://doi.org/10.1021/acs.jproteome.5c00523
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China