Association between estimated glomerular filtration rate and memory function mediated by brain Gray matter volumes: a cross-sectional study using the ADNI database
Higher eGFR levels are positively associated with memory performance, particularly in individuals with MCI, and this association is mediated by GMVs. These findings suggest that renal function may be a critical factor in memory decline risk assessment.
Authors
- Yifeng Du (ORCID: https://orcid.org/0000-0002-4672-6654)
- Lin Song (ORCID: https://orcid.org/0000-0002-7100-1065)
- Jiafeng Wang (ORCID: https://orcid.org/0009-0003-2268-1249)
- Yan Wang (ORCID: https://orcid.org/0000-0002-6460-9160)
- Xiaoyu Wang (ORCID: https://orcid.org/0000-0003-2466-092X)
- Chunyan Li (ORCID: https://orcid.org/0000-0002-9720-2631)
- Qianqian Xie
Institutions
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- BMC Geriatrics
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1186/s12877-025-06326-5
- Citations
- 1
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Natural Science Foundation of Shandong Province
- Shandong First Medical University