Innovations in Antimicrobial Nanotechnology: A Focus on Biosynthesized Silver Nanoparticles and Their Applications
The contemporary area of antimicrobial research is witnessing a transformation with the advent of novel strategies, prominently exemplified by antimicrobial nanoparticles. This review explores this emerging field of antimicrobial nanoparticles, focusing on the efficacy of silver nanoparticles (AgNPs) as powerful means against microbial threats. Addressing the pressing concern of antibiotic resistance, the article underscores the importance of novel approaches. A key highlight is the environment-friendly production of AgNPs derived from various microbial and plant origins, providing sustainable synthesis approaches. The review thoroughly explains how AgNPs combat microbes, utilizing mechanisms such as reactive oxygen species generation and subtle alterations in cellular functions. Beyond theoretical discussions, the practical applications of AgNPs are explored through the study of clinical researches, showcasing their potential in real-world scenarios. By combining insights from these studies, the review underscores AgNPs as promising candidates for effective antimicrobial interventions. It amalgamates eco-friendly synthesis, mechanisms of action, and clinical trial perspectives, positioning AgNPs as valuable players in the ongoing battle against microbial threats. The overview provided here, not only enhances our understanding of AgNPs' antimicrobial capabilities but also points towards future research and development directions. Overall, the review contributes to emphasizing the shift towards innovative, environmentally conscious solutions in the face of escalating microbial challenges.
Authors
- Vinod Kumari (ORCID: https://orcid.org/0000-0002-3091-807X)
- Shashi Meena (ORCID: https://orcid.org/0000-0001-6956-3061)
- Geeta Meena
- Neetu Kachhwaha (ORCID: https://orcid.org/0000-0002-8614-2637)
- Aditya Jain (ORCID: https://orcid.org/0000-0002-9656-6513)
- Pallavi Kaushik (ORCID: https://orcid.org/0000-0003-3566-1418)
- Anu Yadav (ORCID: https://orcid.org/0009-0008-0573-4552)
- Pratap Chand Mali (ORCID: https://orcid.org/0000-0002-2019-0492)
- Ruchi Vyas (ORCID: https://orcid.org/0000-0003-0458-2880)
- Nitesh Gupta (ORCID: https://orcid.org/0000-0003-0471-0133)
- Ram Niwas Jangir (ORCID: https://orcid.org/0000-0002-1146-1983)
Publication Details
- Journal
- Advances in Pharmacology and Pharmacy
- Published
- 2025-08-08
- DOI
- https://doi.org/10.13189/app.2025.130411
- Primary Topic
- Nanoparticles: synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education, India