Sex-specific associations between the triglyceride-glucose index and new-onset hypertension in a hospital employee cohort: evidence from longitudinal annual health examinations

In this retrospective cohort study based on annual health check-up data from hospital employees, we found that the TyG index may be positively associated with the risk of new-onset hypertension, with differences observed between sexes. Further research is needed to validate these findings and address potential confounding and concerns about generalizability.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-08-08
DOI
https://doi.org/10.3389/fendo.2025.1636890
Primary Topic
Blood Pressure and Hypertension Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Sex-specific associations between the triglyceride-glucose index and new-onset hypertension in a hospital employee cohort: evidence from longitudinal annual health examinations

Yuzhan Lin, Shaorong Yan, Cheng Fu, Ruixue Sun et al.
Frontiers in Endocrinology
Blood Pressure and Hypertension Studies
article

Sex-specific associations between the triglyceride-glucose index and new-onset hypertension in a hospital employee cohort: evidence from longitudinal annual health examinations

Yuzhan Lin, Shaorong Yan, Cheng Fu, Ruixue Sun, Jie Cai, Jianghong Qian
article en

Abstract

In this retrospective cohort study based on annual health check-up data from hospital employees, we found that the TyG index may be positively associated with the risk of new-onset hypertension, with differences observed between sexes. Further research is needed to validate these findings and address potential confounding and concerns about generalizability.

Frontiers in EndocrinologyVol. 16
Wenzhou Medical University (CN), Ruian People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 67%
Blood Pressure and Hypertension Studies
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Sex-specific associations between the triglyceride-glucose index and new-onset hypertension in a hospital employee cohort: evidence from longitudinal annual health examinations — Yuzhan Lin, Shaorong Yan, et al. · Frontiers in Endocrinology (2025) | TGRS Research Map | TGRS