Case Report: A man with septic shock developed convulsions

Embolism has variable manifestations in infective endocarditis (IE) and might be misinterpreted in clinical settings. In this study, we reported the case of a 67-year-old man with erysipelas and septic shock who had developed a new onset of blurred vision and subsequently convulsions and multiple cerebral infarctions. Valve vegetations and patent foramen ovale were negative on the first echocardiography. After the neurologic symptom occurred, repeated echocardiography was performed and revealed vegetations on the mitral valve. As the patient had immunological complications, we suggested prolonged antibiotic therapy, but the patient requested an early discharge due to financial concerns. Under such circumstances, administering a long-acting penicillin G via an intramuscular injection once was an alternative therapy before discharge. For patients with bloodstream infection who develop any new onset symptoms related to arterial occlusion, infective endocarditis should be suspected, and repeated echocardiography is necessary.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-08-08
DOI
https://doi.org/10.3389/fmed.2025.1605482
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Case Report: A man with septic shock developed convulsions

Peiliang Gao, Guiying Dong, Yuran Wang, Xueying Fu et al.
Frontiers in Medicine
Infective Endocarditis Diagnosis and Management
article

Case Report: A man with septic shock developed convulsions

Peiliang Gao, Guiying Dong, Yuran Wang, Xueying Fu, Linxiang Huang, Jihong Zhu
article en

Abstract

Embolism has variable manifestations in infective endocarditis (IE) and might be misinterpreted in clinical settings. In this study, we reported the case of a 67-year-old man with erysipelas and septic shock who had developed a new onset of blurred vision and subsequently convulsions and multiple cerebral infarctions. Valve vegetations and patent foramen ovale were negative on the first echocardiography. After the neurologic symptom occurred, repeated echocardiography was performed and revealed vegetations on the mitral valve. As the patient had immunological complications, we suggested prolonged antibiotic therapy, but the patient requested an early discharge due to financial concerns. Under such circumstances, administering a long-acting penicillin G via an intramuscular injection once was an alternative therapy before discharge. For patients with bloodstream infection who develop any new onset symptoms related to arterial occlusion, infective endocarditis should be suspected, and repeated echocardiography is necessary.

Frontiers in MedicineVol. 12
Peking University (CN), Peking University People's Hospital (CN)
National Natural Science Foundation of China, Peking University, Peking University People's Hospital
Good health and well-being
Openalex Percentile: Top 71%
Infective Endocarditis Diagnosis and Management
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Case Report: A man with septic shock developed convulsions — Peiliang Gao, Guiying Dong, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS