S-9-PAHSA ameliorates cognitive decline in a type 2 diabetes mouse model by inhibiting oxidative stress and apoptosis via CAIII modulation
Our study revealed that CAIII was integral to the effects of SP on DRCD, suggesting its potential as a therapeutic target for DRCD.
Authors
- Houguang Zhou (ORCID: https://orcid.org/0000-0002-5550-1166)
- Cheng-Feng He
- Jin‐Hong Lin (ORCID: https://orcid.org/0000-0002-7000-9540)
- Yin Wang (ORCID: https://orcid.org/0000-0002-8137-7496)
- Wen-Jiao Xue
- Jie Ren (ORCID: https://orcid.org/0009-0005-1715-983X)
- Shan-Shan Huang
- Ji‐Chang Xiao (ORCID: https://orcid.org/0000-0001-8881-1796)
- Yanli Zhang (ORCID: https://orcid.org/0000-0002-8942-5325)
- Xinru Wang (ORCID: https://orcid.org/0000-0003-2636-9546)
- Jiantao Wang (ORCID: https://orcid.org/0009-0000-6071-0969)
- Xuechun Wang (ORCID: https://orcid.org/0009-0001-5265-5856)
- Jing-Chun Guo
- Meng Wang (ORCID: https://orcid.org/0000-0001-7648-9955)
Institutions
- Fudan University (CN)
- Shanghai Institute of Organic Chemistry (CN)
- Huashan Hospital (CN)
- Qilu Hospital of Shandong University (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Frontiers in Molecular Neuroscience
- Published
- 2025-08-08
- DOI
- https://doi.org/10.3389/fnmol.2025.1617543
- Primary Topic
- Cholinesterase and Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00