Multivalent display of VP28 on chimeric virus-like particles enhances binding to shrimp target tissues: A novel antiviral strategy against white spot syndrome virus
Multimeric display of VP28 on K5-VLP enhances its binding affinity to shrimp tissues compared to monomeric or peptide forms. This suggests a promising platform for antiviral strategies, including competitive inhibition of WSSV entry and targeted therapeutic delivery in shrimp aquaculture.
Authors
- Monsicha Somrit (ORCID: https://orcid.org/0000-0002-4618-6352)
- Orawan Thongsum (ORCID: https://orcid.org/0009-0002-6916-8840)
- Pitchanee Jariyapong (ORCID: https://orcid.org/0000-0002-4184-6489)
- Somluk Asuvapongpatana (ORCID: https://orcid.org/0000-0003-1594-6555)
- Charoonroj Chotwiwatthanakun (ORCID: https://orcid.org/0000-0001-9137-8444)
- Supawich Boonkua (ORCID: https://orcid.org/0000-0002-2034-7584)
- Wattana Weerachatyanukul (ORCID: https://orcid.org/0000-0002-4365-4800)
- Somkid Jaranathummakul
- Attaboon Wathammawut
Institutions
- Mahidol University (TH)
- Srinakharinwirot University (TH)
- Walailak University (TH)
Publication Details
- Journal
- Veterinary World
- Published
- 2025-08-01
- DOI
- https://doi.org/10.14202/vetworld.2025.2194-2205
- Citations
- 2
- Primary Topic
- Invertebrate Immune Response Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.59