CCDC138 overexpression predicts poor prognosis and highlights ciliopathy-linked mechanisms in uterine corpus endometrial carcinoma
These findings underscore CCDC138's role in UCEC progression, immune modulation, and therapeutic responsiveness, highlighting its potential as a prognostic biomarker and therapeutic target. Its shared relevance in UCEC and ciliopathies suggests broader implications for targeted therapies.
Authors
- Aiping Wang (ORCID: https://orcid.org/0000-0003-2165-6087)
- Fang Yang (ORCID: https://orcid.org/0009-0006-9446-5117)
- Han Fu
- Chunhua Zhang (ORCID: https://orcid.org/0000-0002-0349-390X)
- Li Shi (ORCID: https://orcid.org/0000-0002-3116-8880)
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Shaoxing City Women and Children Hospital (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-08-08
- DOI
- https://doi.org/10.3389/fmolb.2025.1622496
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00