The association between lutein and zeaxanthin intake and multi-level biological aging
Combined LZ intake is associated with attenuated multi-level biological aging [OR (95% CI): 0.93 (0.88, 0.93), <i>P</i> = 0.016] and high LZ intake significantly reduce the risk of all-cause death (<i>P</i> < 0.001), with lutein driving systemic effects via telomere regulation and inflammation suppression. These findings highlight lutein's translatable potential for aging interventions and provide insights for dietary strategies in aging health management.
Authors
- Xiang Jia (ORCID: https://orcid.org/0000-0002-7981-6955)
- Songwen Tan (ORCID: https://orcid.org/0000-0003-0698-4410)
- Chun‐Lei Jiang (ORCID: https://orcid.org/0000-0002-2783-6997)
- Meiyi Tao
- Shengli Sun (ORCID: https://orcid.org/0000-0002-9573-0780)
- Lin Zhang (ORCID: https://orcid.org/0000-0002-5945-5451)
- Shipeng Chen (ORCID: https://orcid.org/0000-0002-4659-6386)
Institutions
- Central South University (CN)
- Changsha Medical University (CN)
- Hunan Normal University (CN)
- General Department of Preventive Medicine (VN)
- Suzhou Research Institute (CN)
- Hunan Provincial People's Hospital (CN)
- Monash University (AU)
- Southeast University (CN)
- Bank of China (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-08-08
- DOI
- https://doi.org/10.3389/fnut.2025.1618158
- Citations
- 1
- Primary Topic
- Antioxidant Activity and Oxidative Stress
- Type
- article
- Field-Weighted Citation Impact
- 0.77