Identification and verification of biomarkers associated with neutrophils in acute myocardial infarction: integrated analysis of bulk RNA-seq, expression quantitative trait loci, and mendelian randomization
There is a causal relationship between neutrophils and AMI. <i>BCL6</i> plays a pivotal role as a key risk gene in neutrophil-mediated damage in AMI. However, more comprehensive studies are needed to determine the molecular mechanism of AMI-related neutrophil coexpressed genes.
Authors
- Xingqing Long
- Peichun He
- Jian Xie (ORCID: https://orcid.org/0000-0003-1381-9704)
- Guoqing Liu (ORCID: https://orcid.org/0000-0002-2221-3651)
- Jiahui Qin (ORCID: https://orcid.org/0000-0003-4021-994X)
- Xiangwen Lv
- Changzhen Fu (ORCID: https://orcid.org/0009-0001-4265-1130)
- Miaomiao Zhu (ORCID: https://orcid.org/0000-0003-1313-5230)
Institutions
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-08-08
- DOI
- https://doi.org/10.3389/fmolb.2025.1614350
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Natural Science Foundation of Guangxi Zhuang Autonomous Region