Define a good prognosis of RNF43 codon 659-mutated and concomitant genomic signatures in CRC: an analysis of the cBioPortal database

In CRC, we found that the G1 cohort had the best prognosis, and patients with <i>RNF43</i> Non-codon 659-mutated, <i>BRAF</i> V600E and MSS had the worst prognosis. This may provide clinical value for patients' further accurate prognosis prediction, curative effect prediction, and follow-up management of patients.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-08-08
DOI
https://doi.org/10.3389/fonc.2025.1608664
Primary Topic
Genetic factors in colorectal cancer
Type
article
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article

Define a good prognosis of RNF43 codon 659-mutated and concomitant genomic signatures in CRC: an analysis of the cBioPortal database

Xueqing Hu, Yingying Huang, Lei Qin, Shuai Zhang et al.
Frontiers in Oncology
Genetic factors in colorectal cancer
article

Define a good prognosis of RNF43 codon 659-mutated and concomitant genomic signatures in CRC: an analysis of the cBioPortal database

Xueqing Hu, Yingying Huang, Lei Qin, Shuai Zhang, Feng Wang, Yunbo Zhao, Liang‐In Lin, Zhongkang Li
article en

Abstract

In CRC, we found that the G1 cohort had the best prognosis, and patients with <i>RNF43</i> Non-codon 659-mutated, <i>BRAF</i> V600E and MSS had the worst prognosis. This may provide clinical value for patients' further accurate prognosis prediction, curative effect prediction, and follow-up management of patients.

Frontiers in OncologyVol. 15
Peking University (CN), Beijing Hospital (CN), Annoroad Gene Technology (China) (CN), Peking University International Hospital (CN), Beijing Tsinghua Chang Gung Hospital (CN)
Good health and well-being
Openalex Percentile: Top 70%
Genetic factors in colorectal cancer
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