The diagnostic accuracy of next-generation sequencing in advanced NSCLC
In the context of high ctDNA TF, blood-based TP-NGS can detect clinically actionable mutations and may effectively replace tissue biopsies when obtaining tumor tissue is impractical.
Authors
- David Shih (ORCID: https://orcid.org/0000-0002-9802-4937)
- Anne W.M. Lee (ORCID: https://orcid.org/0000-0003-2972-0231)
- Isaac Ho
- Dennis Kwok‐Chuen Leung
- Aya El Helali (ORCID: https://orcid.org/0000-0001-6427-114X)
- Ben Man Fei Cheung (ORCID: https://orcid.org/0000-0003-0419-6082)
- Jason W.H. Wong (ORCID: https://orcid.org/0000-0003-2953-7728)
- Matthew Kin-Liang Chiu
- Elaine Yee-Ling Ko (ORCID: https://orcid.org/0009-0005-9442-4756)
- Victor Lee (ORCID: https://orcid.org/0000-0002-6283-978X)
Institutions
- Queen Mary Hospital (CN)
- National Cancer Centre Japan (JP)
- University of Hong Kong - Shenzhen Hospital (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- The Journal of Liquid Biopsy
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1016/j.jlb.2025.100325
- Citations
- 2
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Innovation and Technology Commission