BANSMDA: a computational model for predicting potential microbe-disease associations based on bilinear attention networks and sparse autoencoders

Experiments results showed that BANSMDA achieved superior performance compared to other cutting-edge methods. To further assess its effectiveness, we carried out case studies on two common diseases (including Asthma and Colorectal carcinoma) and two important microbial genera (including <i>Escherichia</i> and <i>Bacteroides</i>), and in the top 20 predicted microbes, there were 19 and 20 having been confirmed by published literature respectively. Besides, in the top 20 predicted diseases, there were 19 and 19 having been confirmed by published literature separately. Therefore, it is easy to conclude that BANSMDA can achieve satisfactory prediction ability.

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Publication Details

Journal
Frontiers in Genetics
Published
2025-08-08
DOI
https://doi.org/10.3389/fgene.2025.1618472
Citations
2
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
1.61

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article

BANSMDA: a computational model for predicting potential microbe-disease associations based on bilinear attention networks and sparse autoencoders

Ona Wu, Bin Zeng, Yu Ge, Shichang Tang et al.
2 citations
Frontiers in Genetics
Gut microbiota and health
1.61
article

BANSMDA: a computational model for predicting potential microbe-disease associations based on bilinear attention networks and sparse autoencoders

Ona Wu, Bin Zeng, Yu Ge, Shichang Tang, Lei Wang, Xianzhi Liu, Mingmin Liang
article en
2 citations

Abstract

Experiments results showed that BANSMDA achieved superior performance compared to other cutting-edge methods. To further assess its effectiveness, we carried out case studies on two common diseases (including Asthma and Colorectal carcinoma) and two important microbial genera (including <i>Escherichia</i> and <i>Bacteroides</i>), and in the top 20 predicted microbes, there were 19 and 20 having been confirmed by published literature respectively. Besides, in the top 20 predicted diseases, there were 19 and 19 having been confirmed by published literature separately. Therefore, it is easy to conclude that BANSMDA can achieve satisfactory prediction ability.

Frontiers in GeneticsVol. 16
Central South University of Forestry and Technology (CN), Central South University (CN), Changsha University (CN), Hunan Vocational College of Safety Technology (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 15%
Gut microbiota and health
1.61
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BANSMDA: a computational model for predicting potential microbe-disease associations based on bilinear attention networks and sparse autoencoders — Ona Wu, Bin Zeng, et al. · Frontiers in Genetics (2025) | TGRS Research Map | TGRS