BANSMDA: a computational model for predicting potential microbe-disease associations based on bilinear attention networks and sparse autoencoders
Experiments results showed that BANSMDA achieved superior performance compared to other cutting-edge methods. To further assess its effectiveness, we carried out case studies on two common diseases (including Asthma and Colorectal carcinoma) and two important microbial genera (including <i>Escherichia</i> and <i>Bacteroides</i>), and in the top 20 predicted microbes, there were 19 and 20 having been confirmed by published literature respectively. Besides, in the top 20 predicted diseases, there were 19 and 19 having been confirmed by published literature separately. Therefore, it is easy to conclude that BANSMDA can achieve satisfactory prediction ability.
Authors
- Ona Wu (ORCID: https://orcid.org/0000-0002-5509-9461)
- Bin Zeng (ORCID: https://orcid.org/0000-0002-1905-8929)
- Yu Ge (ORCID: https://orcid.org/0000-0001-7153-5035)
- Shichang Tang (ORCID: https://orcid.org/0000-0003-0089-7367)
- Lei Wang (ORCID: https://orcid.org/0000-0002-5065-8447)
- Xianzhi Liu (ORCID: https://orcid.org/0000-0002-6646-273X)
- Mingmin Liang
Institutions
- Central South University of Forestry and Technology (CN)
- Central South University (CN)
- Changsha University (CN)
- Hunan Vocational College of Safety Technology (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-08-08
- DOI
- https://doi.org/10.3389/fgene.2025.1618472
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China